What if….. blood cholesterol didn’t matter? The guidelines have changed in the last several years. Turns out, cholesterol is not that bad and can actually be a good thing to shuttle the energy around in your body once you become less dependent on glucose for energy.
Cholesterol is needed for life, which is why we make it in our bodies, and the amount in our cells is very tightly regulated. The complex way the cholesterol is packaged in blood (LDL, HDL, etc) has taken decades to elucidate, but the science is now clear. Total cholesterol is merely correlated with progression of CVD, while LDL (specifically the LDL particles tagged with the ApoB protein) is causally linked to progression of CVD plaques.
Drugs that DO lower ApoB (statins and others) DO slow the progress of plaque formation and reduce the risk of CVD events in randomized controlled trials (RCTs). Drugs that affect things like HDL or total cholesterol without changing ApoB-LDL do not have detectable health benefits, and failed in RCT testing.
A WFPB, low vegetable oil diet where people eat as much as they want reduces LDL cholesterol levels more than any other diet studied, to a level where CVD is essentially non-existent (and well below current US guidelines).
This also is spot on, but it is hard for most folks to move from the "truths" that were preached and believed for years.
Um, I'm not following preachers. I'm reading information gleaned from decades of studies, mostly RCTs involving tens or hundreds of thousands of people, as summarized by entities like the US National Academy of Science, Institute of Medicine, their European counterparts and the WHO.