Thanks, coaly. I agree the series 6V config is better in theory, but at these high capacity (200Ah) and draw rates (340 amps), it seems the much more expensive route. Massive parallelization (such as two 12V batteries with 600 - 700 amp capacities) does make me at least a little nervous, remembering the way our old diesel car used to occasionally explode one of its paralleled batteries. It had the momentary solenoid tie you mentioned in an earlier post. With two permanently paralleled, I'm thinking the chances of surprise explosions should be reduced, but I haven't found much discussion on that subject.
I haven't bought the batteries yet (will probably make it to the store on Friday evening), so if anyone can point me toward a 200+ Ah and > 340A solution in 6V series near that $200 price point, I'd definitely go that route. I'm just not finding it, myself.
There is still some chance I could kill my truck battery overnight, if I leave the trailer plugged in, since the +12V pin on my 7-pin connector is direct battery hot. The battery charger mounted to the trailer self-limits at 10 amps, which won't kill my truck in an hour, but could drag it down over the course of 8+ hours. I could put a relay on the wiring to the battery charger, which will only connect it to the +12V line when I turn on the running lights (I almost always turn on my running lights when towing), but I'm debating if it's worth it. As you already mentioned, my break-away battery is a bigger risk to the truck battery.
Another addition I'm debating is a cheap solar RV charging rig. They sell some at Tractor Supply as low as $25, right next to the batteries. If that's just hanging on those batteries all day every day, chance are they'll be at or near full charge, any time I hook up my truck to roll. I only use this trailer maybe 3x - 5x per year, most of the time it's just sitting.