Yikes. Comparing a sheet of OSB to an engineered I joist with an OSB web is like comparing a pile of toothpicks to an engineered ceiling truss. A sheet of OSB will never, ever transfer loads in an even remotely similar fashion to an I joist with dimensional lumber flanges top and bottom and an OSB web. The folks that designed those wooden floor joists with the OSB web did not include the dimensional lumber flanges for your nailing convenience, this I can promise you.
Please read what I wrote, not what you read. I did not compare OSB to an engineered joist I said it was part of an engineered joist for a reason, when kept in a straight line with 2x4flanges it is extremely rigid.